Ser(i)ous like a tumour

Standard

serious like a tumourI went in for a quick blood test this morning and bumped into the oncologist in the reception. She had news for me.

Remember that clinical trial that I was waiting to hear more about? Well, the doctors who’re conducting it here have suddenly become organised. This morning, they picked up my file and 2 others’ who’re being put forward as possible candidates. She didn’t know much more but said we should hear within a day. Yeah, yeah, I know how these things go so I was pleased to hear that something’s happened but was not going to hold my breath.

There was no waiting.

This afternoon, someone called me about the trial. I’m going in on Friday to sign a consent form (if I agree). Then I have a battery of blood tests, a CT scan, and a tumour tissue sample gets sent to the USA for testing against whatever criteria specifically for this PDL1 drug (I love that it’s called a “programmed death” drug – sounds very Avengers!):

“Under normal conditions, programmed death-ligand 1 (PD-L1) plays an important role in maintaining immune homeostasis. PD-L1 and PD-L2 bind to specific receptors on T cells. When bound to their receptors, cytotoxic T-cell activity is downregulated, thereby protecting normal cells from collateral damage.”

For now, I know that it’s an immunotherapy – not chemotherapy – drug and that…

I’m a potential candidate because:

1) I have a serous tumour rather than a mucinous one. (Don’t ask me. I’m not the specialist but I did find this piece)

“Essentially Mucinous and Serous tumors are cancers of different kinds of ovarian cells. The cells that become Mucinous tumours are those that contain more Mucus. Mucus is believed to make these tumours more aggressive however more mucinous tumours are found at an early stage. These cells are typically the cells lining the ovary.”

I refuse to share the source because they’re mean and want a sign-up before giving up any more free info on cruddy diseases!

2) I had tumour debulking before having chemo (sometimes this happens the other way around) and,

3) I’ve not had chemo in the last 6 – 8 weeks. (I can hardly believe it’s been 10 months.)

The rush is that the trial’s being closed at the end of July – they have to end some or other time – and they want to make sure that they get whichever candidates through the assessment process and starting the trial before it’s too late.

There’s more to find out on Friday but I already know I’ll sign the paperwork. One thing I’ll never ever sign up for again is chemo. The damage it wreaks is just not worth it.

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12 thoughts on “Ser(i)ous like a tumour

  1. Margie Barratt

    Claudine – if you really think that the trial is worth it go for it, just remember it’s not called a “trial” for nothing! every good wish and blessings for you whatever you chose to do

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  2. Great news Claudine! So glad you are going ahead with the trial, I’m sure it can only be a positive decision! Good to be involved in something new and revolutionary that could mean a lot more to you. Will be watching this space!

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    • Thanks, Lori. Yep, for me and for others that follow. Huh, just had the thought that this might be part of my purpose. I’ve never been entirely comfortable with following protocol on this journey. Maybe I was born for this. I’m jumping ahead, though. I’ve still got to be assessed – today.

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  3. Nina Basson

    We have been waiting for this trial for a while now. Results may be positive or not, but from “the battery of tests” that you undergo, something may be shown that will shine a new light.
    I look forward to walk with you along this road.
    Love, mom

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  4. Susan Nel

    Claudine, thank you so much for the updates, I have a special interest in reading them as two of my children have cancer, breast stage III and testicular (tests clear at this stage). My best wishes and positive thoughts are with you.

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  5. Jayne Whittaker

    Good luck with the trials. Positive thoughts and wishes winging their way to you. You are such a role model for so many with your strong will to fight. Hugs to you

    Like

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